Bolodeoku J, Pinkney S, Anyaeche C, Xia A and Bin R
The SMT-100 is a general chemistry point of care testing device similar to the Piccolo Xpress device an example of a microfluidic based platforms, in this study, we performed a precision evaluation of the SMT-100’s Healthy Check and Electrolyte Panel consisting of 14 and 7 analytes and compared with the evaluation carried out in the manufacturer’s laboratory using commercial quality control samples and whole blood samples in our laboratory. From the manufacturers laboratory using commercial quality control samples, there was good precision <10% for all analytes in the healthy check panel (total protein, total cholesterol, total bilirubin, albumin, amylase, alkaline phosphatase, triglyceride, creatinine, gamma glutamyl transferase, glucose, urate, urea, aspartate transaminase, alanine transaminase) and the electrolyte panel (bicarbonate, calcium, phosphate, magnesium, potassium, sodium and chloride). From our laboratory using whole blood samples, the precision was not as tight as that seen using commercial material but there was a good precision <10% for all analytes in the Healthy Check panel, albumin, total protein, total bilirubin, aspartate transaminase, alanine transaminase, amylase, creatinine, urea, creatinine kinase, triglyceride, glucose, calcium apart from globulin with a CV % of 11. The precision of the electrolyte panel analytes, bicarbonate, calcium, phosphate, magnesium, potassium, sodium and chloride was also good with a precision of < 10% apart from potassium with a CV% of 12.1%, after the exclusion of an outlier result, the precision of all the analytes was good (<10%). In addition, these preliminary results on the Chengdu Seamaty SMT-100 showed very reasonable precision results obtained for the general chemistry and liver function analytes comparable to those seen achieved by the Piccolo Xpress.
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