Kartik Syal, Dara Singh, Abhishake Thakur and Avinash Goyal
Introduction: This study was undertaken in Indira Gandhi Medical College, Shimla to evaluate antibiotic sensitivity patterns of various microbes isolated from patients in general Intensive Care Unit. Thus it would serve as a guide to institute empirical antibiotic therapy.
Materials and methods: All patients admitted to general ICU with Endotracheal tube (ETT) in situ were included in this observational study. Those with ETT in place for more than 24 h were excluded from the study. ETT culture samples were collected at 36-48 h and on seventh day of intubation. Culture report and antibiotic susceptibility profile were observed and data hence collected were evaluated.
Results: Out of the total 946 ET culture samples studied 533 (56.3%) showed growth of microorganisms. The number of ET culture isolates increased as the days of intubation increased, i.e., from 45.33% on second day to 70.07% on seventh day. NFG, Klebsiella spp. and Pseudomonas spp. contributed to more than 70% of the ET culture isolates. The ET culture isolates demonstrated high degree of resistance to most of the antibiotics tested.
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