Leopoldo Spadea
Keratoconus (KC) is a progressive, bilateral, but usually
asymmetrical ecstatic corneal disease, characterized by
progressive corneal protrusion and thinning, that leads to
corneal surface distortion. The reported incidence in the general
population varies from 1.3 to 25 per 100,000 per year across
different populations, with a prevalence of 8.8–229 per 100,000.
Onset typically is at puberty with progression of the disease for
10–20 years after which it tends to stabilize. It occurs in all racial
groups and equally affects males and females.
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