A Al-khayyal R, Al-Mousa FA, Attia Am and Ragab AR
Laboratory testing for drugs of abuse has become standard practice in many settings both forensic and clinical. Sending the specimen to any laboratory is waste of time and sometimes the rapid urine testing is a target. A limitation inherent in all urine drug testing is the possibility of sample adulteration or substitution. The aim of the current study is to prove the validity by deeply investigated procedures for urine collection vessels with impeded urine adulteration/substance of abuse (SOA) Test Strips (two types of investigated kits) and evaluation of their total turnaround time and efficacy for cannabinoids, opiates, benzodiazepines, tramadol and amphetamines in-comparison with immunoassay screening and GC-MS confirmatory procedures. Both Investigated Kits have the capability of detecting variable procedures of adulteration by a high efficiency degree. Therefore, SOA tests with rapid releasing results can improve patient management protocol with few percentage of pseudo-positivity/negativity results, unfortunately the operators immediate start the clinical action and realize the limitations of the test and wait for follow-up confirmation testing as appropriate before definitive medico-legal action.
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